College of Medicine
Alli Lab
Led by Abdel Alli · Medicine
What we study
The Alli Lab studies how tiny cell messengers called extracellular vesicles communicate between cells and affect disease processes. They use tools like microscopy, electrophysiology, and protein analysis to explore these mechanisms.
What working here is like
- Wet lab
- Cells in a dish
- Mice
- Coding helps
- Projects
- 2
- Papers
- 5
Current projects
The circadian clock protein BMAL and post-translational regulation of ENaC in the kidney
Investigating how a protein called BMAL affects kidney function in a 24-hour cycle.
Cullin-1, -2, and -3 are upregulated while protein kinase A is downregulated in the kidney of alpha-1 antitrypsin knockout mice
In alpha‑1 antitrypsin knockout mice, kidney proteins cullin‑1, ‑2, and ‑3 were higher and protein kinase A activity was lower. These changes may raise ENaC levels and blood pressure, and future work will explore how cullin‑4A loss drives this effect.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 184
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- A pilot study of urinary biomarkers and kidney injury among agricultural workers
2026 · BMC Nephrology
Tests urinary biomarkers in sugarcane workers to detect kidney issues.
- Role of Ion Channels in the Pathophysiology of SARS-CoV-2
2026 · Viruses
Reviews how ion channels help the COVID-19 virus spread and survive.
Show 3 more papersShow fewer
- Pathogenesis of Calcium Oxalate Kidney Stones, Interactions Among Mitochondria, NADPH Oxidase and Endoplasmic Reticulum
2026 · Biomolecules
Explores how oxygen and calcium oxalate crystals cause kidney stones.
- Single-channel characteristics and regulation of endogenously expressed cation channels in human cardiac microvascular endothelial cells and human aortic endothelial cells
2026 · Biochimica et Biophysica Acta (BBA) - General Subjects
- Dapagliflozin Attenuates NKCC2 Protein Expression and Alleviates Diabetic Kidney Disease in Salt Loaded‐Hypertensive Diabetic Db/Db Mice
2026 · FASEB BioAdvances
Finds that a drug reduces kidney damage in diabetic mice on a high-salt diet.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Abdel Alli hasn't set up this page yet. Their UF Scholars profile lists their publications.