College of Medicine
Martynyuk Laboratory
Led by Anatoly Martynyuk · Anesthesiology
What we study
The lab studies how anesthesia, surgery, and brain injuries in parents affect their offspring's brain development, using rats to explore long-term neurobehavioral effects and potential treatments.
What working here is like
- Wet lab
- Computational
- Rats
- Human participants
- Coding helps
- Projects
- 3
- Papers
- 5
What we're looking for
“We welcome faculty, residents, medical students, and undergrads who are interested in collaboration, training, or just gaining initial experience in basic science laboratory research.”
Current projects
Mechanisms and blood-based biomarkers of intergenerational neurobehavioral effects of general anesthetics
Investigating how anesthesia exposure in parents affects offspring's brain development and behavior.
Neurocognitive consequences of parental traumatic brain injury
Exploring how parental brain injuries impact offspring's cognitive development and behavior.
Show 1 more projectsShow fewer
Perioperative Neurocognitive Disorder in Individuals with a History of Traumatic Brain Injury: A Systematic Review and Meta Analysis
The team reviewed published studies to see if people with past brain injury who have surgery under general anesthesia are more likely to show post‑operative cognitive problems. They screened 27,139 records, kept six studies, and found that the surgery group took longer on the Trail Making Test‑B (p = 0.011).
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 214
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Gut Microbiome Disruption in Traumatic Brain Injury and Therapeutic Potential of Probiotics: A Systematic Review and Meta-Analysis
2026 · Biology
Reviews how brain injuries may change gut bacteria and tests if probiotics help.
- Intergenerational Impact of Maternal Traumatic Brain Injury: Distinct Prenatal and Postnatal Contributions and Pharmacological Rescue
2026
Show 3 more papersShow fewer
- Brain Sex Steroid–Mediated Intergenerational Sex-Specific Neurocognitive Effects of Paternal Sevoflurane Exposure in Rats
2026 · Anesthesia & Analgesia
Finds that male rats exposed to anesthesia have long-term brain changes, possibly linked to hormones.
- Repeated Sevoflurane Exposure Acutely Does Not Disrupt the Gut Microbiome in Young Adult Female Rats
2026 · UF Journal of Undergraduate Research
Checks if repeated anesthesia affects gut bacteria in female rats.
- Contribution of the Brain–Gut–Microbiome Axis to Intergenerational Abnormalities in a Rat Model of Perioperative Neurocognitive Disorder
2025 · Anesthesiology
Shows how gut bacteria may pass on brain problems to future generations in rats.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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