Public Health and Health Professions
Andrew Judge Lab
Led by Andrew R Judge · Physical Therapy
What we study
The lab studies how cancer causes muscle wasting and weakness, focusing on signaling pathways like FoxO and other mediators. They use pre-clinical models and patient biopsies to test treatments for muscle pathology.
What working here is like
- Wet lab
- Clinical
- Human participants
- Projects
- 3
- Papers
- 5
Current projects
Novel therapeutics for cancer cachexia
Developing treatments to combat muscle wasting in cancer patients.
Comparing the morphology and molecular profile of skeletal muscle tissue
Examining muscle tissue from cancer patients to understand tobacco and obesity effects.
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The Complement System and Cancer Cachexia
Studying how the complement system contributes to muscle wasting in cancer.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Dietary supplementation with ursolic acid preserves skeletal muscle mass and strength in mouse models of cancer cachexia
2026 · American Journal of Physiology-Cell Physiology
Shows that ursolic acid dietary supplements help preserve muscle mass and strength in cancer models.
- Murine pancreatic tumors induce pathological remodeling of muscles critical to chewing and swallowing
2026 · American Journal of Physiology-Cell Physiology
Finds that pancreatic cancer weakens chewing and swallowing muscles through different changes in muscle cells.
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- Pancreatic Cancer Disrupts Circadian Patterns of Gene Expression in Cardiorespiratory Muscles
2026 · Journal of Cachexia Sarcopenia and Muscle
Examines how pancreatic cancer disrupts daily rhythms in muscles involved in breathing.
- Dietary Ursolic Acid Supplementation Induces Beneficial Changes in Skeletal Muscle mRNA Expression and Improves Functional Mobility in Older Cats with Sarcopenia: A Proof-of-Concept Study
2026 · Animals
Tests whether ursolic acid dietary supplements improve mobility in older cats with muscle wasting.
- Race-based differences in serum biomarkers for cancer-associated cachexia in a diverse cohort of patients with pancreatic ductal adenocarcinoma
2025 · Communications Medicine
Identifies GDF-15 as a potential biomarker for muscle wasting in Black pancreatic cancer patients.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Andrew R Judge hasn't set up this page yet. Their UF Scholars profile lists their publications.