College of Medicine
Wagle Shukla Lab
Led by Aparna Wagle Shukla · Neurology
What we study
The lab studies movement disorders like Parkinson's and dystonia, using treatments like deep brain stimulation (DBS) and botulinum toxin injections. They also research novel therapies and clinical trials.
What working here is like
- Clinical
- Human participants
- Coding helps
- Projects
- 4
- Papers
- 5
Current projects
Novel applications of oral pharmacological therapies
Explores whether new uses of oral medications can help people with movement disorders such as Parkinson's disease and dystonia.
Transcranial magnetic stimulation research
Studies how transcranial magnetic stimulation, a noninvasive brain stimulation technique, could help treat movement disorders such as Parkinson's disease.
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Twists and Turns of the Neck in Cervical Dystonia and the Impact on Cervical Spine
Researchers reviewed records of 320 patients with neck‑muscle spasms and found 17 (5.3%) developed spine problems that often needed surgery or pain procedures, highlighting the need for long‑term monitoring.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 605
Long-term Outcomes for Blepharospasm and Meige syndrome with DBS surgery
The lab follows 19 patients who had deep brain stimulation surgery for blepharospasm or Meige syndrome. Over 1‑2 years and 6‑9 years after surgery, they measured motor improvement and mood, finding significant motor gains but no change in depression, anxiety, or apathy.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 502
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Beyond the neck: long-term motor and non-motor outcomes of pallidal DBS in craniocervical dystonia
2026 · Dystonia
Follows patients with brain-controlled muscle spasms for years to see how deep brain stimulation helps.
- Cervical Dystonia Treatment with Injections Supplemented by Transcranial Magnetic Stimulation: The D‐ TWIST Pilot Randomized Controlled Trial
2026 · Movement Disorders Clinical Practice
Tests whether magnetic brain stimulation can help botulinum toxin injections last longer for neck spasms.
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- Gait parameters, Imaging features, and CSF tap test in idiopathic Normal Pressure Hydrocephalus (iNPH)
2026 · Parkinsonism & Related Disorders
- How Do Oral Medications, Botulinum Toxin Use, and Treatment Burden Change After Deep Brain Stimulation for Dystonia?
2026 · Parkinsonism & Related Disorders
- Exercise training reshapes motor planning and preparation networks in cervical dystonia
2026 · Brain
Studies how exercise changes brain activity in people with neck spasms.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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