College of Medicine
Bennett Lab
Led by Antonette D Bennett · Biochemistry and Molecular Biology
What we study
The Bennett Lab studies adeno-associated virus (AAV) capsids and their interactions, focusing on structural and biophysical characterization to improve gene delivery for medical applications.
What working here is like
- Wet lab
- Projects
- 3
- Papers
- 5
Current projects
Structural and Biophysical Characterization of AAV Genome Packaging and Ejection for Enhanced Vector Design
Investigating AAV capsid structure and function to improve gene delivery efficiency.
Engineering AAV for safe and efficient gene delivery to the human retina
Engineers variants of adeno-associated virus (AAV), a gene delivery vehicle, to carry therapeutic genes safely and efficiently to the human retina.
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AAV capsids and their cellular interactions
Studies how AAV capsids, the protein shells of a gene therapy virus, interact with cells to deliver genes.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Intracellular trafficking and nuclear compartmentalization of AAV gene delivery
2026 · Molecular Therapy Advances
Maps the path of AAV gene delivery vectors through cells over 72 hours.
- Biophysical and structural insights into AAV genome ejection
2025 · Journal of Virology
Shows how low pH in cells affects the release of viral proteins from AAV capsids.
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- Structural Capsidomics of Single-Stranded DNA Viruses
2025 · Viruses
Reviews structures of icosahedral capsids across single-stranded DNA viruses.
- Mechanisms of AAV neutralization by human alpha-defensins
2025 · PLoS Pathogens
Shows alpha-defensins block AAV infection by binding to viral capsids.
- Mapping the sialic acid-binding sites of LuIII and H-1 parvovirus
2025 · Journal of Virology
Identifies sialic acid as a shared receptor for LuIII and H-1 parvovirus.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Antonette D Bennett hasn't set up this page yet. Their UF Scholars profile lists their publications.