College of Medicine
Boulant Lab
Led by Steeve Boulant · Molecular Genetics and Microbiology
What we study
The lab studies how viruses like rotavirus and norovirus infect and replicate in the gut, focusing on how cell polarity and low oxygen (hypoxia) affect infection and immune responses. They use cell lines, organoids, and patient-derived models to explore these mechanisms.
What working here is like
- Wet lab
- Cells in a dish
- Projects
- 3
- Papers
- 3
Current projects
Hypoxia and viral infection
Investigating how low oxygen in the gut makes cells more vulnerable to viral infections.
Polarized immune response
Studying how gut cells respond differently to pathogens based on their position in the gut lining.
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Cryptosporidium parvum and hypoxia
Exploring how low oxygen affects the infection of the parasite Cryptosporidium parvum in the gut.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Assessment of Epithelial Barrier Integrity by TEER and FITC-Dextran Permeability Assays
2026 · BIO-PROTOCOL
Describes methods to measure epithelial barrier integrity using TEER and FITC-dextran assays.
- Basal IFNλ2/3 signaling is required for ISG expression and viral control in human intestinal epithelial cells
2026 · PLoS Pathogens
Finds that basal IFNλ2/3 signaling is needed for antiviral defense in intestinal cells.
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- Hypoxia Affects Stem Cell Fate in Patient-Derived Ileum Enteroids in a HIF-1α-Dependent Manner
2025 · Cells
Shows that hypoxia affects stem cell fate in intestinal enteroids through HIF-1α.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Steeve Boulant hasn't set up this page yet. Their UF Scholars profile lists their publications.