College of Medicine

Boye Lab

Led by Shannon E Boye · Pediatrics

Auto-generated from UF undergraduate research symposium abstracts

What we study

The Boye Lab studies gene therapies using viral vectors, like adeno-associated viruses (AAVs), to treat inherited eye diseases. They develop new AAV capsids, dual-vector platforms, and CRISPR-based therapies, testing them in animal models and macaques.

What working here is like

  • Wet lab
  • Mice
Projects
5

Current projects

AAV-based gene therapies for LCA1, Usher syndrome 1B, and XLRS

Developing AAV vectors to treat inherited eye diseases like LCA1 and Usher syndrome.

Novel AAV capsids for foveal cone delivery

Creating safer and more efficient AAV capsids to deliver genes to the fovea.

Show 3 more projects

Dual AAV vector platforms for large transgenes

Designs dual AAV gene therapy vectors that split a large gene across two viruses, so large genes can be delivered, with a focus on inherited eye diseases.

AAV-CRISPR therapies for dominant retinal diseases

Using CRISPR with AAVs to treat dominant inherited retinal diseases.

AAV-based therapy for Friedreich’s Ataxia

Developing an AAV-based gene therapy for the eye symptoms of Friedreich’s Ataxia.

Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.

How to reach out

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Open positions

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Boye Lab · Shannon E Boye | JoinLattice