College of Medicine
Byrne Lab
Led by Barry J Byrne · Pediatrics
What we study
The lab studies inherited muscle diseases like Pompe disease and Duchenne muscular dystrophy, using gene therapy to restore muscle function. They develop treatments using viral vectors and test them in clinical trials.
What working here is like
- Wet lab
- Clinical
- Human participants
- Projects
- 2
- Papers
- 2
Current projects
Evaluation of Immune Responses to AAV4E Vector Capsid
Testing immune reactions to a viral vector used in gene therapy for muscle diseases.
Clinical Study of Anti-AAV Antibody Depletion using Efgartigimod alfa-fcab
Research on treating immune responses to viral vectors in DMD patients.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- 90-month Muscle Function and Biomarker Outcomes With Cipaglucosidase Alfa Plus Miglustat (Cipa+Mig) in Adults With Pompe Disease in ATB200-02, an Open-label Phase I/II Study (S7.006)
2026 · Neurology
Tracks muscle function and health markers in Pompe disease patients treated with cipa+mig over 90 months.
- Serotype‐Tailored Midstream and Downstream Operations to Advance the Manufacturing of Adeno‐Associated Viral Vectors
2026 · Biotechnology and Bioengineering
Tests how different ways to break open cells affect making adeno-associated viral vectors for gene therapy.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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