College of Medicine
Mathews Lab
Led by Carol Mathews · Psychiatry
What we study
The Mathews Lab studies the neural and genetic causes of obsessive-compulsive and anxiety disorders, using brain scans, EEG, and psychological tests. They also compare treatments for hoarding disorder.
What working here is like
- Clinical
- Surveys & interviews
- Human participants
- Coding helps
- Projects
- 4
- Papers
- 7
Current projects
The EEG spectrum as a marker of severity, burden, and psychiatric diagnosis
This project examines brain activity patterns to understand how they relate to disorder severity and diagnosis.
Visual perception and attention in the obsessive-compulsive/anxiety spectrum: Neurophysiological characterization, predictive…
This study uses brain scans and computational models to analyze how people with these disorders process information.
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Examining the Comorbidity of Posttraumatic Stress Disorder in Obsessive Compulsive Disorder and Hoarding Disorder
The lab analyzed diagnostic data from 654 participants to see how often PTSD occurs with OCD, hoarding, depression, and anxiety, finding PTSD rates of 27% in OCD, 20% in hoarding, and similar rates in depression and anxiety.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 576
Examining Insight in Neuropsychiatric Disorders using the Brown Assessment of Beliefs Scale
Researchers analyzed scores from the Brown Assessment of Beliefs Scale in 141 people with OCD, hoarding, anxiety, and depression to see if belief rigidity differs by diagnosis. They found no clear differences and plan to study treatment groups next.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 261
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Persistent tic disorders are associated with 17q12 duplications
2026 · Molecular Psychiatry
Finds that a genetic change on chromosome 17 is linked to Tourette syndrome and tic disorders.
- Salient affective scenes compete with concurrent visual responses in the absence of task demands
2026 · Cortex
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- Electronic Health Record–Based Phenotyping for Obsessive-Compulsive Disorder: Algorithm Development and Multicenter Validation Study
2026 · UNC Libraries
Creates and tests a way to spot obsessive-compulsive disorder in medical records.
- Clinical factors predicting tic persistence into adulthood
2026 · Frontiers in Psychiatry
Looks at what makes tics from Tourette syndrome last into adulthood.
- Identifying predictors of treatment response in Hoarding Disorder using machine learning
2026 · Behaviour Research and Therapy
- Tourette syndrome
2026 · Nature Reviews Disease Primers
- Examining Sex-Differentiated Genetic Effects Across Neuropsychiatric and Behavioral Traits
2026 · UNC Libraries
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Carol Mathews hasn't set up this page yet. Their UF Scholars profile lists their publications.