College of Medicine
Casadesus Lab
Led by Gemma Casadesus · Pharmacology and Therapeutics
What we study
The Casadesus Lab studies how the hormone changes of aging, especially menopause, affect brain health and the risk of Alzheimer's disease, including the luteinizing hormone receptor in the brain and genetic differences between the sexes. The goal is treatments that support healthy brain aging.
What working here is like
- Wet lab
- Project
- 1
- Papers
- 4
Current projects
Evaluation of the neuroimmune mechanisms influencing therapeutic targeting potential of the LH/CG receptor in the menopausal and AD brain
Investigating how menopause-related hormones affect Alzheimer's disease risk.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- A murine model of sepsis induces age- and sex-specific chromatin remodeling in myeloid-derived suppressor cells
2026 · Frontiers in Immunology
Studies how sepsis changes gene activity in immune cells, showing differences by age and sex.
- Optimization of Preclinical Rodent Research Models of Human Shock: Part 2 Trauma, Burn, and the Gut Microbiome
2026 · Shock
Reviews rodent models of trauma and burns to better mimic human responses and complications.
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- Temporal impact of sepsis on Alzheimer's disease pathology and neuroinflammation
2025 · Progress in Neurobiology
Examines how sepsis affects brain health in mice, showing sex differences in Alzheimer's risk.
- Optimization of Preclinical Rodent Research Models of Human Shock: Part One Intra-Abdominal Sepsis
2025 · Shock
Discusses how to improve animal models of sepsis to better reflect human conditions.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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