College of Pharmacy
Cui Lab
Led by Lina Cui · Medicinal Chemistry
What we study
The Cui lab studies glycan processing enzymes like heparanase, developing probes and drugs for cancer and age-related diseases. They use organic chemistry, molecular biology, and imaging to explore enzyme activity and create diagnostic tools.
What working here is like
- Wet lab
- Projects
- 2
- Papers
- 5
Current projects
Exploring the precise role of heparanase via small molecule probes
Developing molecular probes to study heparanase activity in cancer and age-related diseases.
Theranostic CAR-T Targeting Senescence in Alzheimer's
Creating CAR-T cells to target senescence in Alzheimer's disease.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Molecular requirements of chromogranin B for the long-sought anion shunter of regulated secretion
2025 · International Journal of Biological Macromolecules
Finds that chromogranin B helps regulate ion flow in cells that release signals.
- Tuning the efficiency of molecular probes via quinone methide-based in situ labeling
2025 · RSC Chemical Biology
Adjusts fluorescent probes to improve their stability and performance in cells.
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- Chemical toolbox to interrogate Heparanase-1 activity
2024 · Current Opinion in Chemical Biology
- Morphological profiling for drug discovery in the era of deep learning
2024 · Briefings in Bioinformatics
Uses deep learning to analyze cell images for drug discovery.
- Design Principle of Heparanase Inhibitors: A Combined In Vitro and In Silico Study
2024 · ACS Medicinal Chemistry Letters
Develops small-molecule inhibitors to block an enzyme linked to cancer and inflammation.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Lina Cui hasn't set up this page yet. Their UF Scholars profile lists their publications.