College of Medicine
Daaka Lab
Led by Yehia Daaka · Physiology and Aging
What we study
The Daaka Lab studies how G protein-coupled and androgen receptors influence development and disease, focusing on cancer progression and vesicle trafficking in infections. They investigate mechanisms like S-nitrosylation and dynamin proteins.
- Projects
- 4
- Papers
- 5
Current projects
Progression of prostate cancer from androgen-dependent to castration-resistant state
Investigating how G protein-coupled receptors and arrestin effectors contribute to prostate cancer progression.
Metastasis of kidney cancer
Examining the role of G protein-coupled receptors and heterotrimeric G proteins in kidney cancer spread.
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Post-translational modification of androgen receptor by S-nitrosylation
Studying how S-nitrosylation affects androgen receptor function in disease progression.
Vesicle trafficking in recurrent urinary tract infections
Researching dynamin's role in vesicle fission during infections.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- DAXX drives de novo lipogenesis and contributes to tumorigenesis
2023 · Nature Communications
Finds that DAXX regulates lipogenic gene expression and tumor growth by interacting with SREBP1 and SREBP2.
- HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers
2023 · Nucleic Acids Research
Shows how histone variant H3.3 controls androgen-induced transcription by regulating AR/BRD4 complex assembly at enhancers.
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- βArrestin1 regulates glucocorticoid receptor mitogenic signaling in castration‐resistant prostate cancer
2022 · The Prostate
Shows that βarrestin1 regulates glucocorticoid receptor mitogenic signaling in castration-resistant prostate cancer.
- Inhibition of Mps1 kinase enhances taxanes efficacy in castration resistant prostate cancer
2022 · Cell Death and Disease
Tests whether inhibiting Mps1 kinase enhances taxane efficacy in castration-resistant prostate cancer.
- Nuclear βArrestin1 regulates androgen receptor function in castration resistant prostate cancer
2021 · Oncogene
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Yehia Daaka hasn't set up this page yet. Their UF Scholars profile lists their publications.