College of Pharmacy
De Moraes Lab
Led by Natalia V De Moraes · Pharmaceutics
What we study
The lab studies how obesity and bariatric surgery affect drug metabolism and elimination, using population pharmacokinetic modeling and physiologically-based pharmacokinetic approaches to design better dosing strategies.
What working here is like
- Computational
- No organisms (data only)
- Coding helps
- Projects
- 3
- Papers
- 5
Current projects
Development of a Population Pharmacokinetic (PopPK) model for Intranasal Epinephrine and Its Application in Pediatric Patients
Creating a model to improve dosing of intranasal epinephrine for pediatric patients.
Optimizing Betamethasone Therapy for Preventing Respiratory Distress Syndrome in Twin Pregnancy
Adjusting betamethasone dosing to prevent respiratory distress in twin pregnancies.
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Development of a physiologically based pharmacokinetic model for a new chemical entity (NCE) to evaluate drug-drug interaction potential
Building a model to assess drug interactions for a new drug candidate.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Enhancing bioavailability of a weakly basic drug through cocrystallization: PBPK modeling of ketoconazole–succinic acid
2026 · European Journal of Pharmaceutics and Biopharmaceutics
- Model‐Informed Dose Selection of Intranasal Epinephrine in Young Children
2026 · The Journal of Clinical Pharmacology
Uses data to create a model for dosing intranasal epinephrine in young children.
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- Exposure‐Matched Intranasal Epinephrine Dosing in Children Is Supported by Pharmacology, Pharmacodynamic Evidence, and Regulatory Review
2026 · The Journal of Clinical Pharmacology
Reviews evidence to support weight-based dosing of intranasal epinephrine in children.
- Mechanistic Prediction of Maternal, Fetal, and Amniotic Fluid Betamethasone Concentrations to Support Dosing Optimization in Pregnancy
2026 · The Journal of Clinical Pharmacology
Builds a model to predict betamethasone levels in pregnant women and fetuses at different ages.
- Optimal dosing of amoxicillin in obese and post-gastric bypass patients using a population pharmacokinetics-pharmacodynamics model approach
2025 · Journal of Antimicrobial Chemotherapy
Studies how obesity and weight-loss surgery affect amoxicillin exposure in patients.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Natalia V De Moraes hasn't set up this page yet. Their UF Scholars profile lists their publications.