Herbert Wertheim College of Engineering
Dickinson Lab
Led by Richard Dickinson · Chemical Engineering
What we study
The Dickinson Lab applies engineering to living cells, combining mathematical models with quantitative experiments and molecular cell biology tools. Recent work looks at how the cell nucleus changes shape and how cells squeeze through tight spaces.
What working here is like
- Wet lab
- Computational
- Coding helps
- Papers
- 5
Recent papers, explained
- Nuclear mechanobiology in confined cell migration
2026 · Nucleus
Reviews how nuclear deformation affects cell migration in confined spaces.
- Hyperwrinkling of the nuclear lamina is associated with attenuated mechanosensitivity in giant nucleated cancer cells
2026 · Science Advances
Finds hyperwrinkled nuclear lamina in giant cancer cells may reduce mechanosensitivity.
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- How the cell nucleus gets in shape
2026 · Nature Chemical Engineering
- Excess surface area of the nuclear lamina enables unhindered cell migration through constrictions
2025 · Science Advances
Shows how nuclear lamina wrinkles and smooths as cells migrate through narrow channels.
- Evidence for Drop‐Like Nuclear Deformation in Sheared Endothelial Monolayers
2025 · Small
Tests whether sheared endothelial cells' nuclei change shape at constant volume and surface area.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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