College of Pharmacy
Zhang Lab
Led by Fan Zhang · Pharmaceutics
What we study
The Zhang Lab develops synthetic nanoplatforms to direct immune cells as 'living therapeutics'. They use materials science, immunology, and cell engineering to study how nanoparticles interact with immune cells and improve drug delivery.
What working here is like
- Wet lab
- Mice
- Coding helps
- Projects
- 2
- Papers
- 5
Current projects
Reveal myeloid cell-mediated targeting through nano-bio interface
Investigating how nanoparticles interact with immune cells to improve drug delivery.
PAMAM Dendrimers Target M-MDSCs as a Potential Platform for Glioblastoma Immunotherapy
Researchers are exploring whether PAMAM dendrimers can be taken up by immune cells that travel to brain tumors, to help deliver drugs across the blood‑brain barrier. Students will help test different dendrimer coatings in mouse tumor models and track where the particles go.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 487
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Engineering lipid nanoparticle surface hydrophobicity to modulate nano-bio interface and enable tissue-selective mRNA delivery
2026 · Biomaterials
- Leveraging endogenous proteins to improve cancer nanomedicine delivery
2026 · Nanoscale
Reviews how endogenous proteins can improve cancer nanomedicine delivery.
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- Investigating the impact of dual-chain coupling on new quality productive forces in leading traditional Chinese medicine enterprises
2026 · Frontiers in Medicine
Tests whether talent-supply chain synergy boosts new quality productive forces in TCM enterprises.
- GPR132 antagonists alleviate atherosclerosis by suppressing M1 polarization and subsequent VSMCs proliferation and migration as revealed by transcriptomic profiling
2026 · Inflammation Research
Shows how GPR132 antagonists reduce atherosclerosis by stopping M1 macrophage polarization and VSMC activity.
- Engineering pH-Responsive Dendrimer–STAT3 Inhibitor Conjugates for Intracellular Delivery
2025 · Biomacromolecules
Builds pH-responsive dendrimer-STAT3 inhibitor conjugates to improve drug delivery.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Fan Zhang hasn't set up this page yet. You can also look them up in the UF directory (search “Fan Zhang”).