College of Dentistry
Frias-Lopez Laboratory
Led by Jorge Frias-Lopez · Oral Biology
What we study
The lab studies how oral microbes interact with the human body, using advanced techniques like metatranscriptomics to understand their functions and roles in health and disease.
What working here is like
- Wet lab
- Computational
- Bacteria & microbes
- Coding helps
- Projects
- 2
- Papers
- 5
Current projects
CRISPR-mediated regulation of bacterial virulence
The lab studies how CRISPR can control bacterial virulence factors in oral microbes.
Functional dynamics of periodontal disease
Research focuses on how microbial communities change during periodontal disease progression.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Porphyromonas gingivalis Vesicles Control Osteoclast–Macrophage Lineage Fate
2026 · International Journal of Molecular Sciences
Tests whether Porphyromonas gingivalis vesicles affect macrophage/osteoclast differentiation.
- A CRISPR array orchestrates virulence and host response in Porphyromonas gingivalis
2026 · Microbiology Spectrum
Shows a CRISPR array in Porphyromonas gingivalis increases biofilm and virulence in mice.
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- Vitamin D deficiency in mice modulates oral microbiome stability over time and leads to changes in host inflammatory gene expression pathways
2026 · Frontiers in Cellular and Infection Microbiology
Finds vitamin D deficiency in mice changes oral microbiome stability and host inflammation over time.
- Transient ecological states shape inter-patient heterogeneity in the periodontal immune–microbial ecosystem
2026 · ISME Communications
Shows how oral immune-microbial ecosystems change over time in patients with periodontal disease.
- CRISPR cas7 influences the host–pathogen interaction of Porphyromonas gingivalis
2025 · Journal of Oral Microbiology
Finds CRISPR-Cas7 in Porphyromonas gingivalis affects its virulence in mice.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Jorge Frias-Lopez hasn't set up this page yet. Their UF Scholars profile lists their publications.