College of Medicine
Crislip Lab
Led by Gene Crislip · Physiology and Aging
What we study
The Crislip Lab studies how diet timing and circadian rhythms affect the kidney and blood pressure in rodents. Recent student work tests time-restricted feeding in young and aged mice on a high-salt diet and measures kidney injury markers.
What working here is like
- Wet lab
- Mice
- Coding helps
- Project
- 1
- Papers
- 5
Current projects
Time Restricted Feeding Does Not Alter Cortical Hypoxia‑Inducible Factor‑1 in Male Adult Mice
Male mice aged 6 and 18 months ate a high-salt diet freely, and some older mice could eat only during an 8-hour window for five weeks. The kidney injury marker KIM-1 was higher with time-restricted feeding and in older mice, while HIF-1α did not change, suggesting it does not drive this kidney scarring.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 345
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Time-restricted feeding for five weeks does not improve renal injury markers in aged male mice
2026 · Physiology
Tests whether eating food only during certain hours helps kidney health in old mice.
- Sex differences in the kidney circadian transcriptome
2026 · Physiology
Finds differences in kidney genes between men and women that may affect health.
Show 3 more papersShow fewer
- Loss of the clock protein PERIOD1 in salt-sensitive hypertension activates tissue-specific Angiotensinogen signaling in male rats
2025 · Physiology
Shows how a clock protein PER1 affects blood pressure and kidney function in men.
- The Benefits of Time-Restricted Feeding on the Kidneys are Blunted in Aged Mice
2025 · Physiology
Tests whether eating food only during certain hours helps kidney health in old mice.
- Sex differences in the adrenal circadian clock: a role for BMAL1 in the regulation of urinary aldosterone excretion and renal electrolyte balance in mice
2024 · American Journal of Physiology-Renal Physiology
Shows sex and time-of-day differences in adrenal circadian clock regulation in mice.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Gene Crislip hasn't set up this page yet. Their UF Scholars profile lists their publications.