College of Medicine
Ghivizzani Gene Therapy Laboratory
Led by Steven C Ghivizzani · Orthopedic Surgery
What we study
The lab uses gene therapy and stem cells to treat musculoskeletal disorders like arthritis and tissue damage. They study viral vectors, stem cells, and genetic factors in diseases like osteoarthritis and achondroplasia.
What working here is like
- Wet lab
- Project
- 1
- Papers
- 4
Current projects
Development of a Novel AAV Vector Capsid Optimized for OA Gene Therapy
Creating improved viral vectors to deliver genes for osteoarthritis treatment.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Osteoarthritis Gene Therapy: A 30‐Year Journey From Concept to Clinical Trials
2026 · Journal of Orthopaedic Research®
Tests whether gene therapy can treat joint diseases by delivering IL-1Ra to joints.
- A phase 1 clinical trial shows safe, sustained, AAV-mediated expression of IL-1Ra in the human osteoarthritic knee joint
2025 · Science Translational Medicine
Tests whether a gene therapy can safely and effectively deliver IL-1Ra to knee joints.
Show 2 more papersShow fewer
- Osteoarthritis gene therapy: Expanding the scope of genetic therapies
2025 · Molecular Therapy
Explores using gene therapy to treat common diseases by delivering therapeutic genes.
- Toxic effects of local anesthetics on rat fibroblasts: An in-vitro study
2024 · Journal of Orthopaedic Science
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Steven C Ghivizzani hasn't set up this page yet. You can also look them up in the UF directory (search “Steven C Ghivizzani”).