Liberal Arts and Sciences
Guo Lab
Led by Zhongwu Guo · Chemistry
What we study
The Guo Lab studies carbohydrates and how they interact with cells, using chemical synthesis and enzyme methods to make natural and artificial sugars, glycopeptides, and glycolipids. They apply these molecules to understand cell‑surface markers and develop new cancer therapies.
What working here is like
- Wet lab
- Papers
- 3
Recent papers, explained
- A New Strategy to Functionalize Exosomes via Enzymatic Engineering of Surface Glycans and its Application to Profile Exosomal Glycans and Endocytosis
2025 · Advanced Science
Developing enzyme‑based methods to modify exosome surface sugars for studying their composition and uptake.
- Monophosphoryl Lipid A–2,4-Dinitrophenylamine Conjugates Are Potent Adjuvants for Carbohydrate and Protein Vaccines
2025 · JACS Au
Creating lipid‑sugar conjugates that boost immune responses to carbohydrate and protein vaccines.
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- Recent research progress in glycosylphosphatidylinositol-anchored protein biosynthesis, chemical/chemoenzymatic synthesis, and interaction with the cell membrane
2024 · Current Opinion in Chemical Biology
Reviewing advances in making GPI‑anchored proteins chemically and enzymatically and studying how they interact with cell membranes.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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