College of Medicine
Jobin Research Lab
Led by Christian Jobin · Medicine
What we study
The Jobin Lab studies how gut bacteria interact with the host, focusing on health and diseases like inflammatory bowel disease (IBD) and colorectal cancer. They use mice and zebrafish in germ-free and gnotobiotic conditions, analyzing microbial genes and RNA-sequences to understand protective and harmful bacterial effects.
What working here is like
- Wet lab
- Mice
- Zebrafish
- Projects
- 4
- Papers
- 5
Current projects
Role of bacterial-derived small molecules in immunotherapy
Investigating how bacteria-derived molecules affect immune responses in cancer treatment.
Interaction between dietary taurine and microbiota sulfur metabolism in the development of colorectal cancer
Exploring how dietary taurine and gut bacteria influence colorectal cancer risk.
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Microbiota, Metabolites, and Colon Neoplasia
Studying how gut microbes and their metabolites contribute to colon cancer development.
Chemical Approaches Toward the Identification, Functional Analysis and Biosynthesis of Small Molecule Cyclomodulins
Identifying and analyzing small molecules that regulate cellular processes.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Combining genotoxic gut bacterial strains increases tumor burden and accelerates onset in a germ-free mouse model of colon carcinogenesis
2026 · Cell Reports
Finds that combining genotoxic gut bacteria strains increases tumor growth and speeds up cancer onset in mice.
- Microbiota and immunotherapy: The birth of a new paradigm?
2026 · Cell Metabolism
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- Defined bacterial consortium highlights the impact of intestinal bacteria on DNA methylation and tumorigenesis
2026 · Genome biology
Shows that a specific gut bacteria strain increases tumor growth and DNA damage in mice with colon cancer.
- Commensal Nakaseomyces glabratus migrates into prostate tumors to accelerate cancer progression
2026 · Nature Cancer
Finds that a gut fungus, Nakaseomyces glabratus, moves into prostate tumors and speeds up cancer growth in mice.
- The E3 ubiquitin ligase HECTD3 controls immune colonic inflammation by restricting MyD88 activation and signaling
2026 · JCI Insight
Found HECTD3, an E3 ubiquitin ligase, controls immune inflammation in ulcerative colitis by regulating MyD88 activation.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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