Health and Human Performance
Laboratory for Neuromuscular Physiology
Led by Lan Wei-LaPierre · Applied Physiology and Kinesiology
What we study
The lab studies how calcium and oxygen-related signals in muscles and nerves cause diseases like ALS and Down syndrome. They use tools like microscopy and electrophysiology to explore these signals and find new treatments.
What working here is like
- Wet lab
- Mice
- Projects
- 3
- Papers
- 5
Current projects
Excitation-contraction coupling and intracellular Ca2+ signaling in skeletal muscle
Studying how calcium moves in muscle cells to understand muscle function and disease.
Mitochondrial Ca2+ and redox biology
Exploring how calcium and oxygen-related signals affect muscle health.
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Using genetic mouse models to identify new therapeutic targets
Using mice to test potential treatments for neuromuscular conditions.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Automated Classification of Store‐Operated Calcium Entry Activity and Disease Conditions in Murine Skeletal Muscle Images Using Machine Learning
2026 · Muscle & Nerve
Uses machine learning to detect muscle disease from images.
- Elevating Circulating L‐Kynurenine Promotes Frailty in Aging Mice
2026 · Journal of Cachexia Sarcopenia and Muscle
Finds that high levels of a chemical linked to aging cause frailty in mice.
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- Fibro‐Adipogenic Progenitor Ablation Triggers Muscle Atrophy Through Cell Death‐Induced Inflammation
2026 · Journal of Cachexia Sarcopenia and Muscle
Shows how removing fat cells in muscle causes muscle loss and inflammation.
- Skeletal Muscle PGC-1 α Alleviates Age-Related Declines in Physical Function by Modulating L-Kynurenine Metabolism
2025 · Physiology
Shows how a protein helps muscles fight aging by breaking down harmful chemicals.
- Mitochondrial diagnostics reveal diffuse impairments in skeletal muscle energetics in aging mice
2025 · Journal of Applied Physiology
Finds that aging weakens muscle energy production in mice, more in females.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Lan Wei-LaPierre hasn't set up this page yet. Their UF Scholars profile lists their publications.