Agricultural and Life Sciences (IFAS)
Larkin Lab
Led by Joseph Larkin III · Microbiology and Cell Science
What we study
The Larkin Lab studies how regulatory T cells (Tregs) control immune responses to prevent autoimmune disease and cancer. They investigate how proteins called SOCS regulate Treg function and explore how gut bacteria influence immune tolerance.
What working here is like
- Wet lab
- Mice
- Bacteria & microbes
- Projects
- 2
- Papers
- 4
Current projects
Mechanisms controlling Treg function
The lab studies how SOCS proteins regulate the activity of regulatory T cells.
Gut microbiota and autoimmune disease
They examine how changes in gut bacteria may influence the development of autoimmune diseases like type 1 diabetes.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis
2025 · Frontiers in Immunology
Tests if SOCS1-KIR peptides reduce inflammation in equine immune cells and eyes.
- Quantification and comparison of anti-AAV9 and anti-AAVrh74 antibodies in plasma and human milk: Implications for AAV-based gene therapy candidacy
2025 · Journal of Neuromuscular Diseases
Measures anti-AAV9 and anti-AAVrh74 antibodies in plasma and human milk.
Show 2 more papersShow fewer
- SOCS1-KIR peptide mimics regulate TLT7 induced inflammatory signatures in murine macrophages 4735
2025 · The Journal of Immunology
Tests whether SOCS1-KIR peptides reduce TLR7-induced inflammation in macrophages.
- Deletion of metal transporter Zip14 reduces major histocompatibility complex II expression in murine small intestinal epithelial cells
2024 · Proceedings of the National Academy of Sciences
Shows that deleting a zinc transporter in mice reduces immune system proteins in gut cells.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Joseph Larkin III hasn't set up this page yet. Their UF Scholars profile lists their publications.