College of Medicine

Licht Laboratory

Led by Jonathan D Licht · Medicine (Hematology and Oncology)

Auto-generated from UF undergraduate research symposium abstracts

What we study

The lab studies how changes in the proteins that package and switch genes on and off (epigenetics) help cause blood cancers such as multiple myeloma and leukemia. Work includes how mutant enzymes like NSD2 change gene regulation and drug sensitivity. It is a cancer-biology lab using cell-based and molecular methods.

Cell & Molecular BiologyCancer Research

What working here is like

  • Wet lab
  • Cells in a dish
  • Coding helps
Projects
2

Current projects

Histone fold mutations in cancer

An NCI-funded project (R01CA266078) on how histone fold mutations drive cancer.

Mutant NSD2 in acute lymphoblastic leukemia

Studies how inhibiting PRC2 can restore sensitivity to glucocorticoid therapy in leukemia cells with mutant NSD2.

Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.

How to reach out

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Open positions

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Licht Laboratory · Jonathan D Licht | JoinLattice