College of Medicine
Maigan Brusko Lab
Led by Maigan A Brusko · Pathology
What we study
The Brusko Lab studies how the thymus (a gland in the chest) produces T cells, which are key immune cells. They investigate how genetics, environment, and childhood development affect these cells and immunity.
What working here is like
- Wet lab
- Projects
- 2
- Papers
- 5
Current projects
Assessment of thymic output in the context of genetics, environmental exposures, and progression to type 1 diabetes
They study how genes and environment affect T cell production and diabetes risk.
Evolution of T cell immunity in blood and tissues over childhood
They track how T cell immunity changes during childhood development.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes
2026 · Cell Reports
Found lymphotoxin-β in pancreas and lymph nodes of diabetes patients using spatial transcriptomics.
- Distinct transcription factors control tissue adaptation and effector function in infant and adult memory T cells
2026 · Nature Immunology
Compared memory T cells in infants and adults using single-cell RNA sequencing.
Show 3 more papersShow fewer
- Imaging mass cytometry reveals functional and immunological changes during type 1 diabetes progression in human pancreata
2026 · Nature Metabolism
Used imaging mass cytometry to study immune changes in pancreas samples from diabetes patients.
- Bootstrap-enhanced regularization addressing multicollinearity and skewness in high-dimensional immunophenotyping data
2026 · BMC Bioinformatics
Develops a method to address multicollinearity and skewness in immunophenotyping data.
- Immune dysregulation and stem-like CD8+ T cell enrichment in type 1 diabetes pancreatic lymph nodes
2026 · Journal of Clinical Investigation
Finds TSCM-like CD8+ cells in type 1 diabetes pancreatic lymph nodes.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Maigan A Brusko hasn't set up this page yet. Their UF Scholars profile lists their publications.