College of Medicine
Martinez-Rivera Lab
Led by Freddyson Martinez-Rivera · Neuroscience
What we study
The Martínez-Rivera Lab studies how the brain weighs drug seeking against punishment, including the roles of two kinds of striatal neurons (D1 and D2 medium spiny neurons) and of extinction learning. It is also testing a lipid-based therapy meant to grow new neurons and slow age-related memory decline.
- Projects
- 2
- Papers
- 5
Current projects
Mitigating Age-Related Cognitive Decline through a First-in-Class Lipid Neurogenic Therapy
Developing a new therapy to improve brain function in older adults.
The impact of extinction and the role of D1 and D2 medium spiny neurons in drug/punishment conflict
Studying how neurons influence behavior in response to punishment and drugs.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Renewal and reacquisition of substance-associated relapse
2026 · Frontiers in Psychology
Explains how memories and stress trigger drug-seeking behaviors in addiction.
- E2F3a transcription factor mediates behavioral, cellular, and DNA-protein regulation of cocaine reward in the nucleus accumbens
2026 · Molecular Psychiatry
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- Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens in male rats
2025 · Nature Communications
Compares gene activity in the brain during cocaine withdrawal and recovery.
- Dopamine D1–D2 signalling in hippocampus arbitrates approach and avoidance
2025 · Nature
- How dopamine guides our social world
2025 · Pharmacological Reviews
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Freddyson Martinez-Rivera hasn't set up this page yet. Their UF Scholars profile lists their publications.