College of Medicine
Swanson Lab
Led by Maurice Swanson · Molecular Genetics and Microbiology
What we study
The Swanson Lab studies how RNA processing affects development and disease, focusing on repetitive DNA sequences and their role in neurological disorders like myotonic dystrophy. They use genetic and biochemical methods to explore RNA binding proteins and tissue regeneration.
What working here is like
- Wet lab
- Mice
- Coding helps
- Projects
- 3
- Papers
- 5
Current projects
Microsatellites, Non-Coding RNAs and RNA-Mediated Disease
Investigating how repetitive DNA expansions cause diseases like myotonic dystrophy by disrupting RNA processing.
Regulation of RNA Processing During Development
Exploring how RNA processing changes during development and how disruptions lead to disease.
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Differential pathology and susceptibility to MBNL loss across mouse muscles in a myotonic dystrophy model
The lab examines how removing the MBNL protein affects different mouse muscles in a model of myotonic dystrophy. Students will collect muscles from knockout mice, look at tissue damage and gene changes, and compare which muscles resemble human disease.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 229
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- SHAPE-MaP-Based Assessment of the Structure of Citrus Tristeza Virus Long Non-Coding RNA
2026 · Viruses
Uses chemical methods to study how citrus virus RNA folds into shape.
- Metabolic reprogramming during human neuron differentiation indicates glutaminase as a key determinant in Fragile X syndrome
2026 · Cell Reports
Shows how a protein helps neurons use amino acids, and how it fails in Fragile X syndrome.
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- RNA-binding protein MBNL2 mitigates neuropathic pain after chemotherapy through destabilizing CCR2 expression in primary sensory neurons
2026 · Neurotherapeutics
Finds that a protein helps reduce pain after chemotherapy by stopping a pain-related gene.
- (Lnc)ing MALAT1-SRSF1 condensates to hypoxia-induced RNA alternative splicing and cancer
2026 · Molecular Cell
- Differential pathology and susceptibility to MBNL loss across muscles in myotonic dystrophy mouse models
2025 · JCI Insight
Compares how two muscle diseases affect different muscles in mice.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Maurice Swanson hasn't set up this page yet. Their UF Scholars profile lists their publications.