Liberal Arts and Sciences
Neurobiology of Addiction Research Lab
Led by Lori Knackstedt · Psychology
What we study
The lab studies how addictive drugs like nicotine, alcohol, and cocaine change brain chemistry, focusing on glutamate neurotransmitter systems. They use methods like western blotting, immunohistochemistry, and microdialysis to understand and treat drug-seeking behaviors.
What working here is like
- Wet lab
- Papers
- 5
Recent papers, explained
- Novel evidence for tirzepatide, a dual GLP-1/GIP receptor agonist, to reduce the motivation for cocaine in rodents
2026 · EBioMedicine
Tests whether tirzepatide reduces cocaine-seeking in rodents.
- The relationship between duration of access to intravenous oxycodone self-administration, economic demand for oxycodone, and cognition in rats
2026 · Psychopharmacology
Shows how oxycodone use affects cognition in rats, worsening with longer access.
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- Predator scent stress reduces oxycodone self-administration and the nucleus accumbens dopamine response to oxycodone in female rats
2025 · Addiction Neuroscience
Shows predator stress reduces oxycodone use and dopamine response in female rats.
- The role of the prelimbic cortex to nucleus accumbens core projection in the reinstatement of cocaine-seeking after cocaine-alcohol polysubstance use
2025 · Neuropsychopharmacology
Finds that polysubstance use changes brain activity during cocaine-seeking.
- The need to incorporate polysubstance use in neuropsychopharmacology research: Biological lessons and new opportunities
2025 · Addiction Neuroscience
Argues for studying polysubstance use in drug research.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Lori Knackstedt hasn't set up this page yet. Their UF Scholars profile lists their publications.