College of Medicine
NeuroTargets Fly Lab
Led by Diego E Rincon-Limas · Neurology
What we study
The lab studies neurodegenerative diseases like Alzheimer's and Parkinson's by using fruit flies to model human conditions. They disrupt or modify fly genes to mimic diseases and find potential treatments.
What working here is like
- Wet lab
- Fruit flies
- Projects
- 4
- Papers
- 5
Current projects
Can SARS-CoV-2 proteins accelerate Abeta pathology in fly and mouse models of AD?
Investigating how COVID-19 proteins might worsen Alzheimer's-like symptoms in flies and mice.
Harnessing new targets and mechanisms mediating AD pathogenesis
Identifying new ways to target Alzheimer's disease mechanisms.
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Nuclear import receptors as modifiers of TDP-43 phase transition and toxicity in FTD/ALS
Studying how certain proteins affect TDP-43 toxicity in frontotemporal dementia and ALS.
Optogenetic systems to regulate light-mediated transcription with spatiotemporal resolution
Developing tools to control gene expression using light in precise ways.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Modulation of host proteostasis by Prevotella corporis via induction of the heat shock response
2026 · Cell Stress and Chaperones
Shows how Prevotella corporis bacteria protect neurons by triggering heat shock responses.
- Progressive Supranuclear Palsy PERK Haplotype B Selectively Translates DLX1 Promoting Tau Toxicity
2026 · Journal of Neuroscience
Compares PERK haplotypes A and B, finding PERK-B promotes DLX1 translation in tauopathy.
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- Activity and State-Dependent Modulation of Salt Taste Behavior Via Pharyngeal Neurons in Drosophila melanogaster
2026 · Neuroscience Insights
Finds how flies adjust to high-salt diets by changing taste sensitivity in pharyngeal neurons.
- Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration
2025 · Frontiers in Molecular Neuroscience
Explains how TCP-1 ring complex helps or harms protein folding in neurodegeneration.
- Infection and chronic disease activate a systemic brain-muscle signaling axis
2024 · Science Immunology
Finds that brain inflammation from infections or neurotoxins causes muscle problems.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Diego E Rincon-Limas hasn't set up this page yet. Their UF Scholars profile lists their publications.