Research lab
Bennett Lab
Led by Richard Bennett
What we study
The Bennett Lab studies how epigenetic regulators of gene activity, such as histone-modifying enzymes, drive cancer, including myeloma. A recent student project grew lung cells carrying a histone H2A mutation to measure how fast they grow, die and move.
What working here is like
- Wet lab
- Cells in a dish
- No coding
- Project
- 1
- Papers
- 5
Current projects
Impact of a Histone H2A Mutation on Cell Biological Properties Related to Cancer
The lab investigates a specific change in a DNA‑wrapping protein that is common in lung cancer. Students grow lung cells with the mutant protein and measure how fast they grow, die, and move compared to normal cells.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 164
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- KDM6A loss enhances oxidative phosphorylation uncovering tissue-level convergent evolution
2026 · The EMBO Journal
Finds that losing KDM6A boosts energy production in tumors, creating a different oxygen environment.
- A Multistep Immune-Competent Genetically Engineered Mouse Model Reveals Phenotypic Plasticity in Uveal Melanoma
2026 · Cancer Research
Creates a new mouse model for uveal melanoma that mimics human disease and immune responses.
Show 3 more papersShow fewer
- KDM6A regulates immune response genes in multiple myeloma
2024 · Blood
Finds that KDM6A helps regulate immune response genes in multiple myeloma.
- NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome
2024 · Blood
Shows how NSD2 in myeloma cells depends on AK2 for survival, linking metabolism to epigenetics.
- Genetic variation drives cancer cell adaptation to ECM stiffness
2024 · Proceedings of the National Academy of Sciences
Shows how cancer cells adapt to different stiffness in their surroundings over time.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Richard Bennett hasn't set up this page yet. You can also look them up in the UF directory (search “Richard Bennett”).