College of Medicine
Renne Lab
Led by Rolf Renne · Molecular Genetics and Microbiology
What we study
The Renne Lab studies Kaposi's Sarcoma-associated Herpesvirus (KSHV) using genomics, genetics, and ribonomics to understand how viral genes and microRNAs contribute to viral biology and cancer. They also coordinate cancer research programs at the UF Health Cancer Center.
What working here is like
- Wet lab
- Computational
- No organisms (data only)
- Coding helps
- Project
- 1
- Papers
- 5
Current projects
Bioinformatically Characterizing KSHV miRNA Splicing Effects on Latency
The student used bioinformatics tools and custom scripts to map where KSHV viral miRNAs bind to RNA and how removing a specific miRNA changes splicing patterns, creating a pipeline for others to study these effects.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 374
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Impaired immune surveillance exposes the germinal center as a niche for gammaherpesvirus-associated B cell lymphomagenesis
2026 · Frontiers in Immunology
Uses mice to study how herpesviruses cause cancer when the immune system is weak.
- Cross‐Species Insights Into Gamma Herpesvirus Transcriptomes: Long‐Read and Multi‐Omics Perspectives
2026 · Journal of Medical Virology
Uses long-read sequencing to study herpesvirus genes across different species.
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- Herpesvirus-encoded lncRNA targets host splicing by interacting with splicing factors
2026 · PLoS Pathogens
Finds a herpesvirus RNA that interacts with host proteins to control cell function.
- A viral circular RNA in Kaposi’s sarcoma-associated herpesvirus modulates viral and host gene expression during latent and lytic replication
2025 · Exploration of Targeted Anti-tumor Therapy
Shows how a viral circular RNA in Kaposi’s sarcoma-associated herpesvirus affects gene expression during infection.
- Targeted Protein Degradation of the Latency‐Associated Nuclear Antigen Evicts Kaposi Sarcoma‐Associated Herpesvirus Episomes From Infected Cells In Vitro
2025 · Journal of Medical Virology
Shows how destroying a herpesvirus protein can remove the virus from infected cells.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Rolf Renne hasn't set up this page yet. Their UF Scholars profile lists their publications.