Public Health and Health Professions
Sarah Judge Lab
Led by Sarah M Judge · Physical Therapy
What we study
The lab studies muscle wasting in cancer patients and models, focusing on signaling pathways like FoxO and other transcriptional networks. They use tissue biopsies, animal models, and cell cultures to identify drivers of muscle loss.
What working here is like
- Wet lab
- Cells in a dish
- Human participants
- Project
- 1
- Papers
- 5
Current projects
Matricellular proteins of the CNN family as regulators of tumor-induced cachexia
Investigating how CNN family proteins drive muscle loss in cancer patients.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Dietary supplementation with ursolic acid preserves skeletal muscle mass and strength in mouse models of cancer cachexia
2026 · American Journal of Physiology-Cell Physiology
Tests whether ursolic acid can slow muscle loss in mice with cancer.
- Murine pancreatic tumors induce pathological remodeling of muscles critical to chewing and swallowing
2026 · American Journal of Physiology-Cell Physiology
Shows pancreatic cancer weakens chewing and swallowing muscles.
Show 3 more papersShow fewer
- Pancreatic Cancer Disrupts Circadian Patterns of Gene Expression in Cardiorespiratory Muscles
2026 · Journal of Cachexia Sarcopenia and Muscle
Finds pancreatic cancer disrupts daily rhythms in heart and breathing muscles.
- The Impact of Edema on Skeletal Muscle Changes among Patients with Pancreatic Ductal Adenocarcinoma
2025 · Cancer Epidemiology Biomarkers & Prevention
Shows how edema affects muscle measurements in pancreatic cancer patients.
- Race-based differences in serum biomarkers for cancer-associated cachexia in a diverse cohort of patients with pancreatic ductal adenocarcinoma
2025 · Communications Medicine
Finds GDF-15 may help detect muscle wasting in Black pancreatic cancer patients.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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