Herbert Wertheim College of Engineering
Soft Tissue Mechanics and Drug Delivery Laboratory
Led by Malisa Sarntinoranont · Mechanical and Aerospace Engineering
What we study
This lab studies how fluids and forces move through soft tissues like the brain, spinal cord and tumors. It uses MRI imaging and computer models to improve drug delivery and understand brain injury.
What working here is like
- Computational
- Wet lab
- Coding helps
- Projects
- 4
- Papers
- 5
Current projects
Mechanical & Flow Environment within Solid Tumors
Builds computer models of solid tumors, including brain tumors, that use MRI to account for leaky blood vessels and abnormal flow, to explain why drugs reach tumors unevenly.
Flow and Drug Delivery in the Brain & Spinal Cord
Builds MRI-based computer models that predict how fluid and drugs flow through the brain and spinal cord, aiming toward personalized therapy for diseases such as epilepsy, Parkinson's and brain tumors.
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Blast traumatic brain injury
Studies how blast waves interact with brain tissue, including bubbles that form and collapse (cavitation), which can cause large local strains linked to blast brain injury.
Flow and Drug Delivery in Plant Vasculature
Develops MRI and 3D fluid-flow modeling tools to measure how fluid moves through plant vessels, such as citrus roots and stems, without chemical pre-treatment.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Early Alignment of Structural Proteins in Tissue Constructs Measured by Polarized Raman Spectroscopy
2026 · Tissue Engineering Part C Methods
Uses polarized Raman spectroscopy to track protein alignment in engineered tissues.
- Measuring alignment of structural proteins in engineered tissue constructs using polarized Raman spectroscopy
2025 · PLoS ONE
Tests whether polarized Raman spectroscopy can measure protein alignment in engineered tissues.
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- Continuous Visualization of Time-Dependent Deformation of a Hydrogel Surface
2025 · Experimental Mechanics
- Heterogeneous Mechanical Stress and Interstitial Fluid Flow Predictions Derived from DCE-MRI for Rat U251N Orthotopic Gliomas
2024 · Annals of Biomedical Engineering
- Determining Rates of Molecular Secretion from Supernatant Concentration Measurements in a 3D-Bioprinted Human Liver Tissue Model
2024 · ACS Biomaterials Science & Engineering
Builds a model to calculate albumin secretion rates from liver tissue samples.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Malisa Sarntinoranont hasn't set up this page yet. Their UF Scholars profile lists their publications.