College of Medicine
Sweeney Lab
Led by Lee Sweeney · Pharmacology and Therapeutics
What we study
The Sweeney Lab studies muscle contraction and disease. They explore how myosins work, discover new drugs like ataluren, and develop gene therapies for muscular dystrophy.
What working here is like
- Wet lab
- Mice
- Project
- 1
- Papers
- 4
Current projects
Gene therapy for muscle disease
Develops gene therapies for muscular dystrophy and age-related muscle loss.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Functional and structural pathologies in skeletal muscle of a rat model of Duchenne muscular dystrophy
2026 · Skeletal Muscle
Creates a rat model of a muscle disease to study how it affects muscle function and structure.
- Direct Observation of Nanometer-Sized Steps of Single Myosin VI Molecules in Living Cells
2026 · Nano Letters
Measures tiny movements of muscle proteins in living cells using a special microscope.
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- Combination S100A1 and ARC gene therapy as a treatment for Duchenne muscular dystrophy cardiomyopathy
2026 · JCI Insight
Tests whether two gene therapies can improve heart problems in mice with a muscle disease.
- Systemic responses to intravenous rAAV administration in boys with Duchenne muscular dystrophy
2026 · Frontiers in Molecular Medicine
Tracks how a gene therapy drug spreads and affects the body in people with a muscle disease.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Lee Sweeney hasn't set up this page yet. You can also look them up in the UF directory (search “Lee Sweeney”).