Herbert Wertheim College of Engineering
Angelini Lab (Soft Matter and Biophysics)
Led by Thomas Angelini · Mechanical and Aerospace Engineering
What we study
This lab studies soft materials and living cells, including how crowds of cells move together. It builds its own instruments, such as 3D printers, and makes its own gels and particles.
What working here is like
- Wet lab
- Building & testing
- Cells in a dish
- No organisms (data only)
- Coding helps
- Projects
- 3
- Papers
- 5
Current projects
NSF TRAILBLAZER project
Develops cell crystals, ordered arrangements of living cells, as a platform for biosensing, in an NSF-funded project.
Single extracellular vesicle sequencing
Sequences individual extracellular vesicles, tiny particles released by cells, using 3D droplet printing in collaboration with another UF lab.
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Characterizing a Mineralizable Composite: 3D Printed Spherical Shells Under Compression
The lab creates a collagen‑microgel material that becomes much stiffer after calcium carbonate mineralization. They 3D‑print spherical shells of different sizes, mineralize them at 37 °C, and are measuring compression strength with a rheometer.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 329
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Thermo-Transitioning Core–Shell Microgels Combine Cohesive Reinforcement and Noncohesive Reconfigurability to Enable 3D Bioprinting and Stabilize Tissues During Incubation
2026 · ACS Biomaterials Science & Engineering
Develops a new microgel system for 3D bioprinting that balances stability and flexibility.
- Biofabrication and biomedical manufacturing research frontiers in the United States
2026 · Bio-Design and Manufacturing
Reviews how biofabrication and biomedical manufacturing can create new medical tools and treatments.
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- Ecosystem technology (ecotech): Harnessing natural processes to address global challenges
2026 · Science Advances
Proposes using natural ecosystem processes to solve global problems like climate change and pollution.
- Elastic moduli and strain-dependent lateral strain to axial strain ratio in semi-dilute polyacrylamide hydrogels
2025 · Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials
- TMIC-55. Tumor mRNA delivery via microgel-chemokine-mRNA (MCM) complex reprograms microglia and induces glioma regression through CCL4-CCR5 axis
2025 · Neuro-Oncology
Tests a microgel vaccine to reprogram immune cells and shrink brain tumors in mice.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Thomas Angelini hasn't set up this page yet. Their UF Scholars profile lists their publications.