College of Dentistry
Toth Lab
Led by Zsolt Toth · Oral Biology
What we study
The Toth Lab studies how herpesviruses keep replicating in the mouth and how a cancer-causing herpesvirus evades the immune system.
What working here is like
- Wet lab
- Projects
- 2
- Papers
- 4
Current projects
Mechanisms sustaining lytic herpesviral infection in the oral cavity
Studies how herpesviruses keep replicating in the mouth, to understand what sustains infection in the oral cavity.
Immune evasion mechanisms by a tumor herpesvirus in the oral cavity
Studies how a cancer-causing herpesvirus avoids the immune system in the mouth, to understand how it persists and causes tumors.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Stage-specific regulation of KSHV infection by HIF-1α
2026 · Journal of Virology
Finds that hypoxia promotes KSHV lytic infection only if HIF-1α is expressed within the first 24 hours post-infection.
- KSHV vIRF3–PKM2 interaction induces SMAD5 acetylation, promoting Kaposi’s sarcoma progression
2026 · Experimental & Molecular Medicine
Shows how KSHV vIRF3 and PKM2 interact to promote Kaposi's sarcoma progression by increasing SMAD5 acetylation.
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- Long-read transcriptomics of caviid gammaherpesvirus 1: compiling a comprehensive RNA atlas
2025 · mSystems
Builds a detailed transcriptomic atlas of CaGHV-1 using long-read RNA sequencing, revealing diverse viral mRNAs and non-coding RNAs.
- Genome-Wide Transcriptional Roles of KSHV Viral Interferon Regulatory Factors in Oral Epithelial Cells
2024 · Viruses
Analyzes how KSHV viral interferon regulatory factors regulate gene expression in oral epithelial cells.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
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