College of Medicine
Vander Kooi Lab
Led by Craig W Vander Kooi · Biochemistry and Molecular Biology
What we study
The Vander Kooi Lab studies how proteins interact to cause biological processes and diseases, using tools like NMR, X-ray crystallography, and mass spectrometry. They focus on hearing loss, glucan kinases, and spatial imaging technologies.
What working here is like
- Wet lab
- Projects
- 3
- Papers
- 5
Current projects
Using the tools of structural biology to describe the mechanism of glucan kinases/phosphatases
Uses structural biology to see how glucan kinases and phosphatases work, with the aim of engineering them for therapeutic use.
Understanding the molecular basis of hearing loss associated with mutations in GIPC3
Investigates how mutations in the GIPC3 gene cause hearing loss, using protein structure and biochemical methods.
Show 1 more projectsShow fewer
Utilizing molecular spatial imaging as co-Director of the Center for Advanced Spatial Biomolecule Research (CASBR)
Developing MALDI-MSI technologies to study biological and pathological processes.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Mapping glycogen accumulation and treatment effect in Pompe disease with saturation transfer MRI
2026 · Translational research
Uses MRI to measure glycogen levels in Pompe disease and track treatment effects.
- Machine-Learning-Based Prediction of Clinical Outcomes in Gliomas Using Glycomic Features
2026 · Computational and Structural Biotechnology Journal
Tests whether glycomic features can predict outcomes in aggressive brain tumors using machine learning.
Show 3 more papersShow fewer
- Mass Spectrometry-Based Spatial Imaging of the Cochlea
2026 · Journal of the American Society for Mass Spectrometry
Develops a method to map chemical changes in the inner ear using mass spectrometry.
- Shaping Human Health and Nutrition Through Innovations in Spatial Metabolism
2026 · Annual Review of Nutrition
Explains how spatial metabolomics reveals how food and metabolism affect health.
- Hyperglycosylation is a metabolic driver of Alzheimer’s disease
2026 · Nature Metabolism
Finds that excess sugar modifications in Alzheimer's brains may drive disease progression.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Craig W Vander Kooi hasn't set up this page yet. You can also look them up in the UF directory (search “Craig W Vander Kooi”).