College of Medicine
Weiner Lab
Led by I. David Weiner · Medicine
What we study
The lab studies how kidneys maintain acid-base balance, focusing on ammonia metabolism and transport. They use animal models, gene studies, and computational methods to understand kidney function and disease progression.
What working here is like
- Wet lab
- Project
- 1
- Papers
- 5
Current projects
Molecular Mechanisms Regulating Ammonia Metabolism
Investigating how ammonia is produced and transported by the kidneys.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Effects of proximal tubule NBCe1-A deletion on collecting duct intercalated cell responses to hypokalemia
2026 · American Journal of Physiology-Renal Physiology
Shows that collecting duct response to low potassium depends on signals from the proximal tubule.
- Uncoupling proximal tubule ammoniagenesis from bicarbonate generation by PCK1 deletion
2026 · American Journal of Physiology-Renal Physiology
Shows ammonium excretion helps regulate acid-base balance indirectly.
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- Lack of a role of NHE4 in renal ammonia metabolism
2025 · American Journal of Physiology-Renal Physiology
Finds that NHE4 does not affect ammonia handling in the kidney.
- Incidence of Immune Checkpoint Inhibitor–Associated Renal Tubular Acidosis
2025 · Kidney International Reports
- Lack of Role of NHE4 in Renal Ammonia Metabolism
2024 · Journal of the American Society of Nephrology
Tests whether deleting NHE4 changes ammonia metabolism in the kidney.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
I. David Weiner hasn't set up this page yet. You can also look them up in the UF directory (search “I. David Weiner”).