Herbert Wertheim College of Engineering
Bolch Lab
Led by Wesley Bolch · Biomedical Engineering
What we study
The Bolch Lab develops computer models to help doctors assess radiation risks in patients. They use 3D patient models and imaging data to improve radiation therapy and imaging safety.
What working here is like
- Computational
- Wet lab
- Coding required
- Projects
- 3
- Papers
- 5
Current projects
Secondary cancer risks in proton versus photon cancer radiotherapy
Comparing radiation risks between proton and photon therapy for cancer patients.
Mesh-Type Histology-Informed Microscale Model of the Human Spleen for Radionuclide Dosimetry
The project builds 3‑D computer models of the human spleen from detailed histology slides. Students help create tiny meshes that let researchers calculate how much radiation dose alpha particles deliver to different spleen tissues.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 419
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3D Reconstruction of Kidney Cortex from H&E-Stained Histology Slides
The lab creates tiny 3D computer models of kidney tissue from microscope slides to help plan radiation therapy. The student aligned 31 slides, marked tubule centers, exported the data, and built two 1 mm³ models of the renal cortex.
From the Spring 2025 UF Undergraduate Research Symposium · abstract book, p. 366
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Enhancements and reference internal dosimetry data for the MOBY whole-body computational phantom of the laboratory mouse
2026 · Physics in Medicine and Biology
Improves a mouse body model with better bones, anatomy, and blood flow for radiation dose studies.
- Electron specific absorbed fractions for the ICRP family of mesh-type reference computational phantoms
2026 · Physics in Medicine and Biology
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- Experimentally Derived Microscale Blood and Lymphatic Vasculature Models for Applications to Radiopharmaceutical Dosimetry
2026 · Microcirculation
Creates detailed blood vessel models from rat tissue to study radiation effects on tiny structures.
- Bridging Organ-Level and Microscale Dosimetry: A 3D Histology-Informed Model of the Renal Cortex for Alpha-Emitting Radionuclides
2026 · International Journal of Radiation Oncology*Biology*Physics
- TetraMorph: Whole-Body, Patient-Specific Mesh Phantoms – Applications to RPT and EBRT Dosimetry
2026 · International Journal of Radiation Oncology*Biology*Physics
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Wesley Bolch hasn't set up this page yet. Their UF Scholars profile lists their publications.