College of Pharmacy
Zheng Lab
Led by Guangrong Zheng · Medicinal Chemistry
What we study
The Zheng Lab designs and synthesizes small molecules to treat diseases like cancer and age-related conditions. They study how these compounds interact with proteins and develop new synthetic methods for drug discovery.
What working here is like
- Wet lab
- Projects
- 3
- Papers
- 4
Current projects
Development of small molecules that can induce targeted protein degradation as potential treatments for cancer
Creating drugs to degrade specific proteins linked to cancer.
Development of senolytic agents, small molecules that can selectively kill senescent cells, as potential treatments for…
Designs and tests small molecules that selectively kill senescent cells, damaged cells that build up with age, as possible treatments for age-related disease.
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Development of radioprotective agents to improve the outcome of cancer radiotherapy or as radiation counter-measure agents
Designs and tests compounds that protect healthy cells from radiation, for cancer radiotherapy or as radiation countermeasures.
Summaries are written by AI in plain language from public symposium abstracts and may be imperfect.
Recent papers, explained
- Fusaric Acid Analogs and Dimers from Marine-Derived Fusarium sp.: Biosynthetic Insights and Chloramphenicol-Enhanced Antibacterial Activity
2026 · Journal of Natural Products
Identifies new marine-derived fungal compounds with antibacterial activity.
- PROTAC-mediated targeting of IKKβ and NR4A1 for AML therapy
2026 · Oncogene
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- A 2-in-1 Strategy for the Discovery of Compact HDAC8 Protac Degraders
2026 · Journal of Medicinal Chemistry
Designs smaller, more effective drug candidates to degrade HDAC8, a protein linked to cancer.
- QuantDSF: an Open-Source Platform for Comprehensive Nano Differential Scanning Fluorimetry Analysis
2026 · Analytical Chemistry
Develops a tool to analyze protein stability and ligand binding from nanoDSF experiments.
Plain-language summaries are AI-written and reviewed by us; check the paper for details.
How to reach out
Guangrong Zheng hasn't set up this page yet. Their UF Scholars profile lists their publications.